![]() In response, vaccination programs against MenW have been initiated in the United Kingdom and Chile ( 1, 3). The ST11 strain was shown by whole-genome sequencing (WGS) to be similar to strains in the South Cone nations of South America ( 2, 4, 5). Historically, MenW accounted for <5% of laboratory-confirmed cases of invasive meningococcal disease (IMD) in England, but in 2014–2015, this serogroup was responsible for 25% of all cases ( 3). ![]() Since 2009–2010, the United Kingdom (England and Wales) has seen an increase in disease caused by 1 endemic hypervirulent strain of MenW that began in older adults and subsequently spread to persons in all age groups ( 3, 4). ![]() Strains belonging to sequence type (ST) 11 are the most prevalent those from the South Cone of South America are part of ST11 but have diversified ( 1, 2). ![]() This serogroup emerged in the South Cone of South America in the mid-2000s and in the United Kingdom in 2009–2010. Neisseria meningitidis serogroup W (MenW) disease was believed to have little epidemic potential before the first international outbreak in 2000, which was related to the Hajj, and has subsequently been described in the African meningitis belt, South Africa, and Saudi Arabia ( 1).
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |